Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347848 | 1.00 | CYP2D6 (0.32) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL9356332 | 0.81 | CYP2D6 (0.41) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL9356064 | 0.81 | CYP2D6 (0.41) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL10588318 | 0.80 | CHRM2 (0.35) | — | |
| SCHEMBL9018638 | 0.80 | CHRM2 (0.38) | — | |
| SCHEMBL5183989 | 0.80 | CHRM2 (0.35) | — | |
| SCHEMBL11206299 | 0.80 | CHRM2 (0.38) | — | |
| SCHEMBL10816002 | 0.80 | CHRM2 (0.38) | — | |
| SCHEMBL10817753 | 0.80 | CHRM2 (0.35) | — | |
| SCHEMBL10651393 | 0.80 | CHRM2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0903353-B1 | Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-0820988-B1 | Imino derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AG (DE) | 2009-07-01 | — | — | EP | disclosed |
| EP-0842944-B1 | Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 | HOECHST AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| EP-0918059-B1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | AVENTIS PHARMA GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-0842945-B1 | Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 | HOECHST AG (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-0918059-A1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-05-26 | — | — | EP | disclosed |
| EP-0688315-B1 | PYRROLIDINE AND OXAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THROMBOCYTE AGGREGATION | HOECHST AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| EP-0905139-A2 | 5 ring heterocyles, process for preparation, use as inhibitors of leukocyte adhesion and pharmaceutical preparations comprising them | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-03-31 | — | — | EP | disclosed |
| EP-0503561-A2 | Method for the diastereoselective reductive pinacol coupling of homochiral alpha aminoaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-16 | — | — | EP | disclosed |
| EP-0475184-A1 | Process for the production of peptides by solid phase synthesis | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0449079-A2 | Hydantoin derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0435059-A1 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | disclosed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0131226-B1 | DERIVATIVES OF 2-AZABICYCLO(3.1.0)HEXANE-3-CARBOXYLIC ACID, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THEM, AND THEIR USE; 2-AZABICYCLO(3.1.0)HEXANE DERIVATIVES AS INTERMEDIATES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |
| EP-0131226-A2 | Derivatives of 2-azabicyclo(3.1.0)hexane-3-carboxylic acid, process for their preparation, agents containing them, and their use; 2-azabicyclo(3.1.0)hexane derivatives as intermediates and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |
| EP-0131226-A2 | Derivatives of 2-azabicyclo(3.1.0)hexane-3-carboxylic acid, process for their preparation, agents containing them, and their use; 2-azabicyclo(3.1.0)hexane derivatives as intermediates and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |