Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356064 | 1.00 | CYP2D6 (0.41) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL10347848 | 0.81 | CYP2D6 (0.32) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL9352597 | 0.81 | ARG1 (0.37) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL4019622 | 0.81 | CYP2D6 (0.32) | CYP2D6LMNABLMALOX15TSHR | |
| SCHEMBL10753923 | 0.77 | — | — | |
| SCHEMBL5183989 | 0.75 | CHRM2 (0.35) | — | |
| SCHEMBL11206299 | 0.75 | CHRM2 (0.38) | — | |
| SCHEMBL6578062 | 0.75 | CHRM2 (0.35) | — | |
| SCHEMBL10816002 | 0.75 | CHRM2 (0.38) | — | |
| SCHEMBL10588318 | 0.75 | CHRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299513-B1 | Azetidine derivatives, compositions and their use | FIDIA GEORGETOWN INST (US) | 1994-10-05 | — | — | EP | claimed |