Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | PADI3 | Q9ULW8 | 5/20 | 0.47 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.45 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658418 | 0.85 | ALDH1A1 (0.54) | ALDH1A1LMNA | |
| SCHEMBL6418674 | 0.78 | AOC3 (0.67) | AOC3ERAP2ERAP1LNPEPCFD | |
| SCHEMBL5726547 | 0.76 | CFD (0.71) | AOC3CFDEPHX2NR1H4 | |
| SCHEMBL5713256 | 0.75 | PTPN1 (0.41) | SRCALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL30259900 | 0.75 | AOC3 (0.72) | AOC3ERAP2ERAP1LNPEPCFD | |
| SCHEMBL14365887 | 0.75 | AOC3 (0.63) | AOC3ERAP2ERAP1LNPEPCFD | |
| SCHEMBL6230841 | 0.75 | AOC3 (0.63) | AOC3ERAP2ERAP1LNPEPCFD | |
| SCHEMBL18459819 | 0.75 | ALDH1A1 (0.66) | AOC3ALDH1A1LMNA | |
| SCHEMBL18638228 | 0.74 | ERAP2 (0.67) | AOC3ERAP2ERAP1LNPEPCFD | |
| SCHEMBL31061520 | 0.74 | AOC3 (0.75) | AOC3ERAP2ERAP1LNPEPCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482379-B2 | Propenoyl hydrazides | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-20050256058-A1 | Propenoyl hydrazides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256058-A1 | Propenoyl hydrazides | DNPEP, HPN, PREP | AOC3 2472/4885ERAP2 163/4885ERAP1 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.