Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.60 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.59 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.59 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552725 | 0.89 | ALDH1A1 (0.80) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL4021293 | 0.85 | ALDH1A1 (1.00) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL5175917 | 0.85 | ALDH1A1 (1.00) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL4021288 | 0.85 | ALDH1A1 (1.00) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL5158355 | 0.80 | ALDH1A1 (0.89) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL10336384 | 0.80 | ALDH1A1 (0.89) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL27311354 | 0.80 | ALDH1A1 (0.89) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL31705223 | 0.80 | SENP1 (0.53) | ALDH1A1LMNACYP2D6CYP2C19AOC3 | |
| SCHEMBL26761468 | 0.78 | ALDH1A1 (0.85) | ALDH1A1LMNACYP2D6CYP2C19TAAR1 | |
| SCHEMBL6418674 | 0.78 | AOC3 (0.67) | ALDH1A1LMNAAOC3PADI3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482379-B2 | Propenoyl hydrazides | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| US-20050256058-A1 | Propenoyl hydrazides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256058-A1 | Propenoyl hydrazides | DNPEP, HPN, PREP | ALDH1A1 2687/4885LMNA 2599/4885CYP2D6 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.