Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711082 | 0.83 | CYP1A2 (0.49) | CYP1A2TSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL13960699 | 0.79 | HSD17B10 (0.48) | HSD17B10ALDH1A1GAAMAPTIDO1 | |
| SCHEMBL4018688 | 0.79 | HSD17B10 (0.48) | HSD17B10ALDH1A1GAAMAPTIDO1 | |
| SCHEMBL4018690 | 0.79 | HSD17B10 (0.48) | HSD17B10ALDH1A1GAAMAPTIDO1 | |
| SCHEMBL6978728 | 0.78 | CREBBP (0.63) | TSHRBRD4CREBBP | |
| SCHEMBL30417761 | 0.78 | CREBBP (0.63) | TSHRBRD4CREBBP | |
| SCHEMBL11307625 | 0.76 | ITGB1 (0.55) | CYP1A2TSHRHSD17B10ALDH1A1GAA | |
| SCHEMBL11627496 | 0.76 | MTNR1A (0.57) | CYP1A2TSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL6715404 | 0.75 | MTNR1A (0.51) | CYP1A2TSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL11200246 | 0.75 | CYP1A2 (0.49) | CYP1A2TSHRHSD17B10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015179-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |