Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022478 | 1.00 | KDM2B (0.31) | KDM2BRORCMGLL | |
| SCHEMBL4779149 | 0.88 | — | — | |
| SCHEMBL4022530 | 0.86 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4023878 | 0.86 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL13721304 | 0.86 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4022223 | 0.85 | KIF11 (0.32) | KDM2B | |
| SCHEMBL4024718 | 0.85 | KDM4E (0.34) | KDM2BMGLL | |
| SCHEMBL4021154 | 0.85 | KDM4E (0.34) | KDM2BMGLL | |
| SCHEMBL13721491 | 0.85 | KDM4E (0.34) | KDM2BMGLL | |
| SCHEMBL4025503 | 0.84 | KIF11 (0.34) | KDM2BMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |