Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022223 | 0.90 | KIF11 (0.32) | KIF11KDM2BOPRD1OPRM1MC4R | |
| SCHEMBL4022530 | 0.89 | KDM2B (0.34) | KIF11KDM2BMGLLMC4RMEN1 | |
| SCHEMBL13721304 | 0.89 | KDM2B (0.34) | KIF11KDM2BMGLLMC4RMEN1 | |
| SCHEMBL4023878 | 0.89 | KDM2B (0.34) | KIF11KDM2BMGLLMC4RMEN1 | |
| SCHEMBL4020419 | 0.89 | KDM2B (0.32) | KIF11KDM2BOPRD1OPRM1MGLL | |
| SCHEMBL4749303 | 0.87 | KDM2B (0.31) | KIF11KDM2B | |
| SCHEMBL4749092 | 0.87 | KDM2B (0.31) | KIF11KDM2B | |
| SCHEMBL4749288 | 0.87 | KDM2B (0.31) | KIF11KDM2B | |
| SCHEMBL4749084 | 0.87 | KDM2B (0.31) | KIF11KDM2B | |
| SCHEMBL4018647 | 0.86 | KDM2B (0.33) | KDM2BMGLLMC4RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |