SCHEMBL4020804

SCHEMBL4020804

Cc1ccc(S(=O)(=O)OC[C@H](O)COCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA4 P22748 1/20 0.50
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4020810 1.00 CA1 (0.50) CA1CA2CA7CA9CA4
SCHEMBL2338952 1.00 CA1 (0.50) CA1CA2CA7CA9CA4
SCHEMBL3648172 0.88 CA1 (0.40) CA1CA2CA7CA9CA4
SCHEMBL3648169 0.88 CA1 (0.40) CA1CA2CA7CA9CA4
SCHEMBL7429844 0.85 AR (0.55) CA1CA2CA7CA9CA4
SCHEMBL11686413 0.85 AR (0.55) CA1CA2CA7CA9CA4
SCHEMBL28581384 0.85 ALDH1A1 (0.43) CA1CA2CA7CA9CA4
SCHEMBL13841806 0.85 ALDH1A1 (0.43) CA1CA2CA7CA9CA4
SCHEMBL28581383 0.85 ALDH1A1 (0.43) CA1CA2CA7CA9CA4
SCHEMBL7925816 0.85 GAA (0.49) CA2CA7CA9ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120092035-A Cationically curable composition 日产化学株式会社 2025-06-03 CN disclosed
EP-2963043-B1 TETRAHYDROIMIDAZO[1,5-D][1,4]OXAZEPINE DERIVATIVE EISAI R&D MAN CO LTD (JP) 2018-05-30 EP disclosed
CN-105008375-B Tetrahydroimidazo [1,5-d ] [1,4] oxazepine derivatives 卫材R&D管理有限公司 2016-12-28 CN disclosed
US-9458176-B2 Tetrahydroimidazo(1,5-D)[1,4]oxazepine derivative EISAI R&D MANAGEMENT CO., LTD. (JP) 2016-10-04 US disclosed
WO-2016033190-A1 RADIOTRACER COMPOUNDS EISAI, INC. (JP) 2016-03-03 WO disclosed
EP-2963043-A1 TETRAHYDROIMIDAZO[1,5-D][1,4]OXAZEPINE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2016-01-06 EP disclosed
CN-105008375-A Tetrahydroimidazo [1,5-d ] [1,4] oxazepine derivatives WEI CAIR 2015-10-28 CN disclosed
US-20140243316-A1 Tetrahydroimidazo(1,5-D)[1,4]Oxazepine Derivative EISAI R&D MANAGEMENT CO., LTD. (JP) 2014-08-28 US disclosed
US-7569579-B2 for inhibition of HIV replication and treatment of acquired immune deficiency syndrome SMITHKLINE BEECHAM CORPORATION (US) 2009-08-04 US disclosed
EP-1569934-B1 CYCLOPROPYL COMPOUNDS AS CCR5 ANTAGONISTS SMITHKLINE BEECHAM CORP (US) 2008-01-23 EP disclosed
US-5942387-A Combinatorial process for preparing substituted thiophene libraries ELI LILLY AND COMPANY (US) 1999-08-24 US disclosed
EP-0880558-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1998-12-02 EP disclosed
WO-1998046631-A1 COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR ELI LILLY AND COMPANY (US) 1998-10-22 WO disclosed
WO-1998046786-A1 COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS ELI LILLY AND COMPANY (US) 1998-10-22 WO disclosed
WO-1998008839-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed
WO-1998008813-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed
EP-0816310-A2 Scavenger assisted combinatorial process for preparing libraries of tertiary amine compounds ELI LILLY AND COMPANY (US) 1998-01-07 EP disclosed
WO-1997026300-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES ELI LILLY AND COMPANY (US) 1997-07-24 WO disclosed
US-5532225-A TREATMENT OF HERPES VIRUS SRI INTERNATIONAL (US) 1996-07-02 US disclosed
EP-0062918-B1 IMIDAZOLE DERIVATIVES G.D. Searle & Co. (US) 1986-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243316-A1 Tetrahydroimidazo(1,5-D)[1,4]Oxazepine Derivative GRM2, GRM1, GRIA2 CA1 659/4885CA2 465/4885CA7 4312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.