SCHEMBL2338952

SCHEMBL2338952

Cc1ccc(S(=O)(=O)OCC(O)COCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA4 P22748 1/20 0.50
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4020810 1.00 CA1 (0.50) CA1CA2CA7CA9CA4
SCHEMBL4020804 1.00 CA1 (0.50) CA1CA2CA7CA9CA4
SCHEMBL3648172 0.88 CA1 (0.40) CA1CA2CA7CA9CA4
SCHEMBL3648169 0.88 CA1 (0.40) CA1CA2CA7CA9CA4
SCHEMBL7429844 0.85 AR (0.55) CA1CA2CA7CA9CA4
SCHEMBL11686413 0.85 AR (0.55) CA1CA2CA7CA9CA4
SCHEMBL28581384 0.85 ALDH1A1 (0.43) CA1CA2CA7CA9CA4
SCHEMBL13841806 0.85 ALDH1A1 (0.43) CA1CA2CA7CA9CA4
SCHEMBL28581383 0.85 ALDH1A1 (0.43) CA1CA2CA7CA9CA4
SCHEMBL7925816 0.85 GAA (0.49) CA2CA7CA9ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1813987-B1 SULFONIC-ESTER-CONTAINING COMPOSITION FOR FORMATION OF ANTIREFLECTION FILM FOR LITHOGRAPHY NISSAN CHEMICAL IND LTD (JP) 2011-08-24 EP claimed
US-12630544-B2 Compound, α-synuclein aggregate binder, and use thereof National Institutes for Quantum Science and Technology (JP) 2026-05-19 US disclosed
CN-120092035-A Cationically curable composition 日产化学株式会社 2025-06-03 CN disclosed
US-20230399323-A1 NOVEL COMPOUND, a-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-12-14 US disclosed
EP-4206200-A1 NOVEL COMPOUND, ALPHA-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF National Institutes for Quantum Science and Technology (JP) 2023-07-05 EP disclosed
CN-115989029-A Novel compound, alpha synuclein aggregate binding agent, and use thereof 国立研究开发法人量子科学技术研究开发机构 2023-04-18 CN disclosed
WO-2022045093-A1 NOVEL COMPOUND, α-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF 国立研究開発法人量子科学技術研究開発機構 2022-03-03 WO disclosed
WO-2012136305-A1 PROCESS FOR IMPROVING THE ELECTRICAL PARAMETERS IN CAPACITORS COMPRISING PEDOT/PSS AS SOLID ELECTROLYTE, BY MEANS OF ADDITIVES HERAEUS PRECIOUS METALS GMBH & CO. KG (DE) 2012-10-11 WO disclosed
EP-1813987-B1 SULFONIC-ESTER-CONTAINING COMPOSITION FOR FORMATION OF ANTIREFLECTION FILM FOR LITHOGRAPHY NISSAN CHEMICAL IND LTD (JP) 2011-08-24 EP disclosed
US-7615331-B2 Photosensitive resin composition, production method of cured relief pattern using the same and semiconductor device FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-5242943-A Administering as beta adrenoceptor blocking agents Louis, William J. (AU) 1993-09-07 US disclosed
US-5187293-A Blood platelet activating factor inhibitors HOFFMANN-LA ROCHE INC. (US) 1993-02-16 US disclosed
US-5051445-A Cardiovascular disorders such as antiarrhythmia or cardiotonic agents, adrenergic blocking agents Louis, William J. (AU) 1991-09-24 US disclosed
EP-0177515-B1 3-AMINOPROPYLOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Louis, William John (AU) 1989-05-31 EP disclosed
EP-0147768-B1 GLYCERIN DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1989-02-08 EP disclosed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US disclosed
EP-0177515-A4 3-AMINOPROPYLOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. SANDOZ LTD (CH) 1986-09-23 EP disclosed
EP-0177515-A1 3-AMINOPROPYLOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. SANDOZ LTD (CH) 1986-04-16 EP disclosed
WO-1985004403-A1 3-AMINOPROPYLOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANDOZ LTD. (CH) 1985-10-10 WO disclosed
US-4182911-A BETA-ADRENERGIC BLOCKING AGENTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399323-A1 NOVEL COMPOUND, a-SYNUCLEIN AGGREGATE BINDER, AND USE THEREOF SNCA, PARK7, ATXN2L CA1 3364/4885CA2 3080/4885CA7 4118/4885
US-12630544-B2 Compound, α-synuclein aggregate binder, and use thereof SNCA, PARK7, MAPT CA1 3244/4885CA2 3217/4885CA7 3920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.