Hydrochloric Acid

SCHEMBL4020921

Cc1cc(C)c(-c2c3nc(c(-c4c(C)cc(C)cc4C)c4ccc([nH]4)c(-c4c(C)cc(C)cc4C)c4nc(c(-c5c(C)cc(C)cc5C)c5ccc2[nH]5)C=C4)C=C3)c(C)c1.[Cl-].[Cl-].[Cl-].[Mn+3]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE BDKRB2 CHRM1 CHRM2 CHRM3 CHRNA1 CHRNB1 CHRND CHRNE CHRNG GUCY1A1 GUCY1A2 GUCY1B1 GUCY1B2 NAMPT PTAFR SLC10A2 SLC6A2 SLC6A3 TACR1 dacA dacB dacC ftsI mrcA mrcB mrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	TERT	O14746	5/20	0.45

▸	TOP1	P11387	2/20	0.42

▸	ABCG2	Q9UNQ0	1/20	0.40

▸	CYCS	P99999	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Hydrochloric Acid SCHEMBL30558879	1.00	TERT (0.45)	TERTTOP1ABCG2CYCS
SCHEMBL29558385	0.96	TERT (0.47)	TERTTOP1ABCG2CYCS
SCHEMBL949016	0.96	TERT (0.47)	TERTTOP1ABCG2CYCS
Magnesium SCHEMBL29489413	0.95	TERT (0.46)	TERTTOP1ABCG2CYCS
SCHEMBL29501686	0.95	TERT (0.46)	TERTTOP1ABCG2CYCS
SCHEMBL30368182	0.95	TERT (0.46)	TERTTOP1ABCG2CYCS
SCHEMBL15995094	0.95	TERT (0.46)	TERTTOP1ABCG2CYCS
SCHEMBL29812943	0.95	TERT (0.46)	TERTTOP1ABCG2CYCS
Hydrochloric Acid SCHEMBL4020916	0.93	TERT (0.45)	TERTTOP1ABCG2CYCS
SCHEMBL5013677	0.87	TERT (0.41)	TERTTOP1ABCG2CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009088404-A1	PROCESSES FOR THE PREPARATION OF ARTEMISININ AN ITS PRECURSORS	AMYRIS BIOTECHNOLOGIES, INC. (US)	2009-07-16	—	—	WO	disclosed