Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR1F | P30939 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13504541 | 0.86 | TSHR (0.48) | HTR6 | |
| SCHEMBL4021090 | 0.86 | HTR6 (0.55) | HTR6BCHEDRD3DRD2HTR1A | |
| SCHEMBL4018793 | 0.86 | HTR6 (0.69) | HTR6DRD3DRD2HTR1AHTR1D | |
| SCHEMBL3622623 | 0.81 | HTR6 (0.52) | HTR6BCHEDRD3DRD2HTR1A | |
| SCHEMBL3619679 | 0.76 | HTR6 (0.61) | HTR6DRD3DRD2 | |
| Trifluoroacetic Acid SCHEMBL3621025 | 0.74 | HTR6 (0.46) | HTR6BCHEDRD3DRD2HTR1A | |
| SCHEMBL2086144 | 0.74 | HTR6 (0.71) | HTR6DRD3DRD2HTR1AHTR1D | |
| SCHEMBL4018797 | 0.74 | HTR6 (0.71) | HTR6DRD3DRD2HTR1AHTR1D | |
| SCHEMBL13504542 | 0.73 | TSHR (0.49) | HTR6DRD2HTR7 | |
| SCHEMBL3621334 | 0.73 | HTR6 (0.69) | HTR6DRD3DRD2HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | claimed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | claimed |