Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022692 | 0.89 | CYP1A2 (0.43) | TRPM8MAPTMITFLMNASMN1; SMN2 | |
| SCHEMBL4028514 | 0.89 | CYP1A2 (0.43) | TRPM8MAPTMITFLMNASMN1; SMN2 | |
| SCHEMBL4017695 | 0.89 | CYP1A2 (0.43) | TRPM8MAPTMITFLMNASMN1; SMN2 | |
| SCHEMBL5739515 | 0.89 | MEN1 (0.45) | TRPM8MAPTMITFLMNASMN1; SMN2 | |
| SCHEMBL4022147 | 0.84 | METAP1 (0.51) | LMNASMN1; SMN2L3MBTL1HTTFFAR1 | |
| SCHEMBL4017115 | 0.80 | GPR39 (0.41) | SMN1; SMN2L3MBTL1HTTFFAR1MAPK14 | |
| SCHEMBL2835717 | 0.77 | TRPM8 (0.34) | TRPM8MAPK14 | |
| SCHEMBL15626310 | 0.75 | FFAR1 (0.38) | TRPM8CYP1A2FFAR1LIMK1MAPK14 | |
| SCHEMBL21171439 | 0.75 | FFAR1 (0.38) | TRPM8CYP1A2FFAR1LIMK1MAPK14 | |
| SCHEMBL4016503 | 0.75 | HRH3 (0.39) | TRPM8CYP1A2FFAR1LIMK1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504001-B1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF SE (DE) | 2009-04-15 | — | — | EP | disclosed |
| US-7320975-B2 | 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | disclosed |
| US-20050107401-A1 | 2- (2-pyridyl) -5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1504001-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF Aktiengesellschaft (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003070721-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107401-A1 | 2- (2-pyridyl) -5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | HAAO, HAO1, DAO | TRPM8 4084/4885MAPT 4275/4885MITF 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.