Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024531 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KMT2AGAAEGFRLMNA | |
| SCHEMBL4021369 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KMT2AGAAEGFRLMNA | |
| SCHEMBL4019381 | 0.83 | KMT2A (0.46) | ALDH1A1KMT2AGAALMNASIGMAR1 | |
| SCHEMBL4019373 | 0.83 | KMT2A (0.46) | ALDH1A1KMT2AGAALMNASIGMAR1 | |
| SCHEMBL4772340 | 0.83 | KMT2A (0.48) | ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL4026548 | 0.83 | KMT2A (0.46) | ALDH1A1KMT2AGAALMNASIGMAR1 | |
| SCHEMBL4024734 | 0.80 | NTRK1 (0.43) | ALDH1A1KMT2AGAALMNAKDM4E | |
| SCHEMBL4774189 | 0.80 | NTRK1 (0.43) | ALDH1A1KMT2AGAALMNAKDM4E | |
| SCHEMBL4019229 | 0.80 | NTRK1 (0.43) | ALDH1A1KMT2AGAALMNAKDM4E | |
| SCHEMBL4024282 | 0.79 | SLC18A3 (0.45) | ALDH1A1KMT2AGAALMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |