SCHEMBL4021595

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1939965	0.88	KDR (0.50)	KDRKMT2AMEN1TDP1KDM4E
	SCHEMBL1942121	0.86	KDR (0.48)	KDRKMT2AMEN1TDP1KDM4E
	SCHEMBL1941665	0.84	KDR (0.46)	KDRKMT2AMEN1TDP1KDM4E
	SCHEMBL1496254	0.83	KDR (0.48)	KDRKMT2AMEN1KDM4EHTT
	SCHEMBL4015002	0.83	KDR (0.71)	KDRKMT2AMEN1TDP1KDM4E
	SCHEMBL2908904	0.82	KDR (0.46)	KDRKMT2AMEN1KDM4EHTT
	SCHEMBL1496291	0.81	KDM4E (0.47)	KDRKMT2AMEN1KDM4EHTT
	SCHEMBL1785676	0.81	KDR (0.53)	KDRKMT2ATDP1KDM4EHTT
	SCHEMBL4020286	0.81	KDR (0.58)	KDRKMT2AMEN1TDP1KDM4E
	SCHEMBL2916686	0.80	NPC1 (0.54)	KDRKMT2AMEN1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.