Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2913390 | 0.93 | KDR (0.45) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL1496254 | 0.85 | KDR (0.48) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL2909264 | 0.83 | LMNA (0.50) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL2916664 | 0.83 | LMNA (0.49) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL1496291 | 0.83 | KDM4E (0.47) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL4021595 | 0.82 | KDR (0.55) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL1496285 | 0.81 | KDM4E (0.44) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL2916686 | 0.80 | NPC1 (0.54) | KDRKDM4EHTTKMT2AMEN1 | |
| SCHEMBL1496351 | 0.78 | LMNA (0.52) | KDRKDM4EHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1496333 | 0.78 | KDR (0.46) | KDRKDM4EHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854787-B1 | NOVEL CYCLIC COMPOUND HAVING QUINOLYLALKYLTHIO GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2010-09-01 | — | — | EP | claimed |