Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24417412 | 0.77 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL24416958 | 0.72 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL29713462 | 0.70 | KDM4E (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL21873113 | 0.70 | KDM4E (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL12498325 | 0.69 | EGLN2 (0.36) | CYP11B1TDO2IDO1 | |
| SCHEMBL6425402 | 0.69 | OPRM1 (0.39) | IDO1 | |
| SCHEMBL17868286 | 0.66 | TDO2 (0.39) | TDO2IDO1 | |
| SCHEMBL29672973 | 0.66 | KDM4E (0.40) | CYP11B1CYP11B2TDO2IDO1 | |
| SCHEMBL2596919 | 0.66 | TDO2 (0.36) | TDO2IDO1 | |
| SCHEMBL2881406 | 0.66 | CCR1 (0.35) | TDO2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | disclosed |
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | disclosed |
| US-6953807-B2 | 4-substituted-picolinic acid amide derivatives useful as fungicides | BAYER CROPSCIENCE S.A. (FR) | 2005-10-11 | — | — | US | disclosed |
| US-20040142977-A1 | 4-Substituted-picolinic acid amide derivatives useful as fungicides | BAYER SAS (FR) | 2004-07-22 | — | — | US | disclosed |
| EP-1404666-A1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003006456-A1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE S.A. (FR) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142977-A1 | 4-Substituted-picolinic acid amide derivatives useful as fungicides | CYP4X1, CYP4B1, CYP51A1 | CYP11B1 212/4885CYP11B2 243/4885TDO2 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.