SCHEMBL4022352

SCHEMBL4022352

c1ccc2c(c1)c1ccccc1c1[nH]cnc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 2/20 0.48
PRNP P04156 2/20 0.48
HPGD P15428 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
PARP1 P09874 6/20 0.45
PDPK1 O15530 1/20 0.45
CA12 O43570 1/20 0.45
ALOX15 P16050 1/20 0.45
CA9 Q16790 1/20 0.45
TNKS2 Q9H2K2 1/20 0.45
KDM4E B2RXH2 2/20 0.44
ABL1 P00519 2/20 0.44
DYRK1A Q13627 2/20 0.44
AURKA O14965 1/20 0.44
DAPK3 O43293 1/20 0.44
JAK2 O60674 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678942 1.00 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL30674414 0.86 KDM4A (0.44) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL2294487 0.81 PDE4A (0.51) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL31095920 0.79 PDE4A (0.50) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL22946772 0.78 KIF11 (0.44) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL17969622 0.77 PDE4A (0.48) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL19035434 0.76 LIMK1 (0.38) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL4102738 0.75 CHEK1 (0.60) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL19741339 0.75 PARP1 (0.53) SMN1; SMN2ALDH1A1PRNPHPGDMEN1
SCHEMBL31095909 0.75 PDE4A (0.47) SMN1; SMN2ALDH1A1PRNPHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372862-A A kind of triphenyl phenanthro- imidazoles aerotex and its preparation method and application 湘潭大学 2019-10-25 CN claimed
CN-110317198-A A kind of phenothiazine compounds and its preparation method and application 信阳师范学院 2019-10-11 CN claimed
CN-110156988-A A kind of phenanthro- imidazole radicals aerotex and its preparation method and application 湘潭大学 2019-08-23 CN claimed
CN-105837630-B A kind of decyl imidazoles blue emission luminous organic material and preparation method thereof 中国广州分析测试中心 2017-11-14 CN claimed
CN-106220612-A Indole-containing phenanthro [9,10-d ] imidazole derivative and synthesis and application thereof 大连理工大学 2016-12-14 CN claimed
CN-1659174-A Hydrogen storage method, hydrogen clathrate and process for producing the same KURITA WATER IND LTD (JP) 2005-08-24 CN claimed
JP-5273616-A None JP disclosed
EP-4656637-A1 COMPOUND, AND LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, LIGHTING DEVICE AND PHOTOSENSITIZER EACH CONTAINING SAME Toray Industries, Inc. (JP) 2025-12-03 EP disclosed
US-20240324264-A1 OLED WITH HYBRID EMISSIVE LAYER THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-09-26 US disclosed
WO-2024157868-A1 COMPOUND, AND LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, LIGHTING DEVICE AND PHOTOSENSITIZER EACH CONTAINING SAME 東レ株式会社 2024-08-02 WO disclosed
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2024-07-18 US disclosed
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) 2024-07-18 US disclosed
US-12029055-B2 OLED with hybrid emissive layer THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2024-07-02 US disclosed
US-5256718-A Flame retardant polyamide thermoplastic resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-26 US disclosed
JP-H05273616-A TERTIARY NONLINEAR OPTICAL MATERIAL UBE IND LTD 1993-10-22 JP disclosed
EP-0442465-A2 Thermoplastic resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-08-21 EP disclosed
US-4607073-A Molding polyamide composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-08-19 US disclosed
EP-0011115-B1 ANTIINFLAMMATORY 2-SUBSTITUTED-1H-PHENANTHRO(9,10-D)IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-01-20 EP disclosed
US-4215135-A Antiinflammatory 2-substituted-1H-phenanthro[9,10-d]imidazoles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed
EP-0011115-A1 Antiinflammatory 2-substituted-1H-phenanthro(9,10-d)imidazoles, their preparation and pharmaceutical compositions containing them E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239754-A1 PHENANTHROIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF PAH, HTR3D, CYP3A4 SMN1; SMN2 4787/4885ALDH1A1 135/4885PRNP 3307/4885
US-12029055-B2 OLED with hybrid emissive layer S1PR4, S1PR1, S1PR2 SMN1; SMN2 1058/4885ALDH1A1 2347/4885PRNP 2888/4885
US-20240324264-A1 OLED WITH HYBRID EMISSIVE LAYER S1PR4, S1PR2, S1PR1 SMN1; SMN2 997/4885ALDH1A1 2646/4885PRNP 2555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.