SCHEMBL2294487

SCHEMBL2294487

c1cnc2c(c1)c1nc[nH]c1c1cccnc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.51
PDE4B Q07343 1/20 0.51
PDE4C Q08493 1/20 0.51
PDE4D Q08499 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.47
NPC1 O15118 1/20 0.47
HSP90AA1 P07900 1/20 0.47
PARP1 P09874 3/20 0.41
ALDH1A1 P00352 3/20 0.41
PRNP P04156 2/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ABL1 P00519 1/20 0.40
RAD52 P43351 1/20 0.40
RIN1 Q13671 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31095920 0.98 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DL3MBTL1
SCHEMBL27869175 0.98 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DL3MBTL1
SCHEMBL31095909 0.93 PDE4A (0.47) PDE4APDE4BPDE4CPDE4DL3MBTL1
SCHEMBL17969622 0.88 PDE4A (0.48) PDE4APDE4BPDE4CPDE4DL3MBTL1
SCHEMBL4022352 0.81 SMN1; SMN2 (0.48) PDE4APDE4BPDE4CPDE4DPARP1
SCHEMBL29678942 0.81 SMN1; SMN2 (0.48) PDE4APDE4BPDE4CPDE4DPARP1
SCHEMBL9740120 0.79 MAPT (0.43) PDE4APDE4BPDE4CPDE4DL3MBTL1
SCHEMBL10829012 0.75 PARP1 (0.47) L3MBTL1NPC1HSP90AA1PARP1ALDH1A1
SCHEMBL29849953 0.75 HSP90AA1 (0.67) L3MBTL1NPC1HSP90AA1PARP1ALDH1A1
SCHEMBL4009364 0.75 HSP90AA1 (0.67) L3MBTL1NPC1HSP90AA1PARP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250375511-A1 METHOD FOR TREATING CONDITIONS ASSOCIATED WITH HYPERPROLIFERATING CELLS COMPRISING COMBINED ADMINISTRATION OF INFECTIOUS AGENTS AND METAL CATIONS THERALASE TECH INC (CA) 2025-12-11 US claimed
US-20250375458-A1 COMPOSITIONS AND METHODS TO COMBAT MULTIDRUG-RESISTANT AND PERSISTENT T-CELL-MEDIATED, ONCOLOGICAL AND INFECTIOUS DISEASES THERALASE TECH INC (CA) 2025-12-11 US claimed
US-20250114456-A1 ENHANCED IMMUNOTHERAPEUTIC METHOD COMPRISING COMBINED ADMINISTRATION OF PHOTODYNAMIC / RADIOTHERAPEUTIC COMPOUNDS AND IMMUNOTHERAPEUTIC AGENTS THERALASE TECHNOLOGIES, INC. (CA) 2025-04-10 US claimed
CN-110256501-B Liver cancer cell inhibitor and preparation method thereof 玉林师范学院 2024-09-10 CN claimed
US-11697707-B2 Chemical sensors based on carbon nanotubes functionalised by conjugated polymers for analysis in aqueous medium ECOLE POLYTECHNIQUE (FR) 2023-07-11 US claimed
CN-115835742-A High-quality tin-based perovskite thin film, preparation method thereof and photoelectric device 华中科技大学 2023-03-21 CN claimed
CN-113105640-B Europium coordination polymer capable of emitting red fluorescence under excitation of near-visible light, and preparation method and application thereof 首都师范大学 2022-05-20 CN claimed
EP-2976347-B1 METAL-BASED COORDINATION COMPLEXES AS PHOTODYNAMIC COMPOUNDS AND THEIR USE MCFARLAND SHERRI ANN (US) 2022-01-19 EP claimed
US-20210130540-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-05-06 US claimed
US-10766915-B2 Metal-based coordination complexes as photodynamic compounds and their use MCFARLAND SHERRI ANN (CA) 2020-09-08 US claimed
EP-3609881-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM Ecole Polytechnique (FR) 2020-02-19 EP claimed
US-10115908-B2 Imidazole[4,5-F][1,10]phenanthroline derivatives, method of preparing the same, and use thereof BOE TECHNOLOGY GROUP CO., LTD. (CN) 2018-10-30 US claimed
WO-2018189479-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM ECOLE POLYTECHNIQUE (FR) 2018-10-18 WO claimed
EP-3053922-B1 IMIDAZOLE [4,5-F][1,10]PHENANTHROLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF BOE TECHNOLOGY GROUP CO LTD (CN) 2018-05-09 EP claimed
EP-3053922-A1 IMIDAZOLE [4,5-F][1,10]PHENANTHROLINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF BOE Technology Group Co., Ltd. (CN) 2016-08-10 EP claimed
US-20150263295-A1 IMIDAZOLE[4,5-F][1,10]PHENANTHROLINE DERIVATIVES, METHOD OF PREPARING THE SAME, AND USE THEREOF BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-09-17 US claimed
US-7989089-B2 2-(9-anthryl)imidazo[4,5-f]-[1,10]phenanthroline (2) or 2-(2-pyridyl)imidazo[4,5-f]-[1,10]phenanthroline (4) LG DISPLAY CO., LTD. (KR) 2011-08-02 US claimed
US-12545794-B2 Security feature, printing ink, document of value, and manufacturing method GIESECKE+DEVRIENT CURRENCY TECHNOLOGY GMBH (DE) 2026-02-10 US disclosed
CN-102617617-A Imidazo[4,5-f]1,10-phenanthroline cerium complex and preparation method thereof UNIV SHENYANG CHEMICAL TECH 2012-08-01 CN disclosed
WO-2010102393-A1 2-INDOLYL IMIDAZO [4,5-D]PHENANTHROLINE DERIVATIVES AND THEIR USE TO INHIBIT ANGIOGENESIS LORUS THERAPEUTICS INC. (CA) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375458-A1 COMPOSITIONS AND METHODS TO COMBAT MULTIDRUG-RESISTANT AND PERSISTENT T-CELL-MEDIATED, ONCOLOGICAL AND INFECTIOUS DISEASES CD4, TPMT, SLC11A2 PDE4A 1602/4885PDE4B 1151/4885PDE4C 1981/4885
US-12545794-B2 Security feature, printing ink, document of value, and manufacturing method MRPL9, MRPL19, MRPS9 PDE4A 3612/4885PDE4B 3576/4885PDE4C 3639/4885
US-20150263295-A1 IMIDAZOLE[4,5-F][1,10]PHENANTHROLINE DERIVATIVES, METHOD OF PREPARING THE SAME, AND USE THEREOF PAH, AHR, H1-5 PDE4A 4446/4885PDE4B 4397/4885PDE4C 4601/4885
US-10766915-B2 Metal-based coordination complexes as photodynamic compounds and their use PIN1, PPIF, PPOX PDE4A 3304/4885PDE4B 3734/4885PDE4C 3183/4885
US-20250114456-A1 ENHANCED IMMUNOTHERAPEUTIC METHOD COMPRISING COMBINED ADMINISTRATION OF PHOTODYNAMIC / RADIOTHERAPEUTIC COMPOUNDS AND IMMUNOTHERAPEUTIC AGENTS PDCD1, CD47, CD274 PDE4A 3768/4885PDE4B 3473/4885PDE4C 3784/4885
US-10115908-B2 Imidazole[4,5-F][1,10]phenanthroline derivatives, method of preparing the same, and use thereof PAH, AHR, H1-5 PDE4A 4446/4885PDE4B 4397/4885PDE4C 4601/4885
US-20250375511-A1 METHOD FOR TREATING CONDITIONS ASSOCIATED WITH HYPERPROLIFERATING CELLS COMPRISING COMBINED ADMINISTRATION OF INFECTIOUS AGENTS AND METAL CATIONS NFATC1, PCNA, PHPT1 PDE4A 3346/4885PDE4B 3404/4885PDE4C 3099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.