SCHEMBL4022387

SCHEMBL4022387

CCCCOC(=O)C(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CCC(C)(C)N(C)C1(C)C)C1CCC(C)(C)N(C)C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
CNR2 P34972 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193901 0.83 GAA (0.36) GAAPKMHTT
SCHEMBL3632901 0.80 GAA (0.34) GAAPKMHTT
SCHEMBL1719502 0.78 GAA (0.35) GAAPKMHTTCNR2
SCHEMBL16305038 0.78 GAA (0.33) GAAPKMHTT
SCHEMBL9231435 0.77 GAA (0.32) GAAPKMHTT
SCHEMBL28872498 0.77 GAA (0.37) GAAPKMHTTCNR2
SCHEMBL7106655 0.77 VCAM1 (0.30)
SCHEMBL27974159 0.76 GAA (0.39) GAAPKMHTT
SCHEMBL3418928 0.76 GAA (0.32) GAAPKMHTT
SCHEMBL28530376 0.76 NR5A2 (0.36) GAAPKMHTTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1213283-B1 Biphenyl-substituted triazines as light stabilisers CIBA HOLDING INC (CH) 2009-04-29 EP disclosed
US-7410940-B2 Antioxidants for the stabilization of surfactant formulations CIBA SPECIALTY CHEMICALS CORP. (US) 2008-08-12 US disclosed
US-20080108540-A1 Antioxidants for the stabilization of formulations comprising surfactants HUEGLIN DIETMAR 2008-05-08 US disclosed
US-6841670-B2 High thermal stability, are used as stabilizers for organic polymers to counter damage thereto caused by light, oxygen and heat, as light stabilizers for textile fiber materials and as sunscreens for the human skin. CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-01-11 US disclosed
US-20030148916-A1 Antioxidants for the stabilization of formulations comprising surfactants HUGLIN DIETMAR (DE) 2003-08-07 US disclosed
US-20030045444-A1 Biphenyl-substituted triazines FLETCHER IAN JOHN (CH) 2003-03-06 US disclosed
US-6468958-B2 LIGHT, OXYGEN AND HEAT RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-22 US disclosed
EP-0815089-B1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER CIBA SC HOLDING AG (CH) 2002-09-25 EP disclosed
EP-1213283-A2 Biphenyl-substituted triazines as light stabilisers Ciba SC Holding AG (CH) 2002-06-12 EP disclosed
US-20020042022-A1 Alkylphenylbisacylphosphine oxides and photoinitiator mixtures LEPPARD DAVID GEORGE (CH) 2002-04-11 US disclosed
US-6020528-A Alkylphenylbisacylphosphine oxides and photoinitiator mixtures CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-02-01 US disclosed
US-6013703-A AN ORGANIC ZINC COMPOUND AND AN ORGANIC ALUMINIUM, SODIUM OR POTASSIUM COMPOUND IN COMBINATION WITH A STERICALLY HINDERED AMINES AS THE STABILIZER MIXTURE FOR POLYVINYL CHLORIDE; LEAD-FREE WITCO VINYL ADDITIVES GMBH (DE) 2000-01-11 US disclosed
EP-0955355-A2 Antioxidants for the stabilization of formulations comprising surfactants Ciba SC Holding AG (CH) 1999-11-10 EP disclosed
US-5942290-A MOLECULAR COMPLEX OF A MONO-, BIS- OR TRIACYLPHOSPHINE OXIDE ASSOCIATED WITH AN ALPHA-HYDROXY KETONE IN CRYSTALLINE FORM BY WAY OF HYDROGEN BONDING; PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-24 US disclosed
US-5852090-A Norbornene-substituted bisphenol antioxidants CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-22 US disclosed
US-5814688-A POLAR, ADSORPTIVE MATERIAL IN FORM OF FIBERS OR PARTICLES, AND POLAR ANTISTATIC MIXTURE OF POLAR ORGANIC COMPOUND AND SALT OF PROTIC ACID CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-29 US disclosed
US-5804622-A STERIC HINDRANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-08 US disclosed
EP-0815089-A1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER Ciba SC Holding AG (CH) 1998-01-07 EP disclosed
WO-1996028431-A1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-09-19 WO disclosed
US-5550242-A REACTION CARRIED OUT IN INERT ORGANIC SOLVENT IN PRESENCE OF SOLID ALKALI METAL HYDROXIDE OR A MIXTURE OF HYDROXIDE AND WATER; AVOIDS USE OF PHASE TRANSFER CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030045444-A1 Biphenyl-substituted triazines TYR, CYP1B1, NFE2L2 GAA 3171/4885PKM 4185/4885HTT 1931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.