SCHEMBL4022565

SCHEMBL4022565

Cc1c(F)cccc1[C@H]1[C@@H](C(=O)c2cccc(O)c2)CN(C2CC(C)(C)NC(C)(C)C2)C[C@@H]1c1[c]cccc1O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4021730 0.87 L3MBTL1 (0.37) L3MBTL1
SCHEMBL4020359 0.87 MC4R (0.33)
SCHEMBL4772489 0.83 NPSR1 (0.33)
SCHEMBL4028913 0.81 MC4R (0.30)
SCHEMBL4028221 0.80 KDM2B (0.32)
SCHEMBL4778094 0.80 KDM2B (0.32)
SCHEMBL4022123 0.80 RORC (0.41)
SCHEMBL4022033 0.80 KDM2B (0.32)
SCHEMBL4021615 0.79 HCRTR2 (0.31)
SCHEMBL4774163 0.79 KDM2B (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572814-B2 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds CYTOKINETICS, INCORPORATED (US) 2009-08-11 US claimed