Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | IL2 | P60568 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022581 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AAAK1RBP4 | |
| SCHEMBL4024037 | 0.96 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AAAK1RBP4 | |
| SCHEMBL4024035 | 0.96 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AAAK1RBP4 | |
| SCHEMBL4749448 | 0.94 | EED (0.34) | ALDH1A1MEN1KMT2APARP10EED | |
| SCHEMBL4022374 | 0.90 | KDM4E (0.37) | ALDH1A1PARP10EEDOPRM1 | |
| SCHEMBL4022370 | 0.90 | KDM4E (0.37) | ALDH1A1PARP10EEDOPRM1 | |
| SCHEMBL5634573 | 0.88 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AAAK1RBP4 | |
| SCHEMBL5635105 | 0.86 | EED (0.31) | ALDH1A1EEDOPRM1 | |
| SCHEMBL4027956 | 0.85 | KDM2B (0.43) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL4027951 | 0.85 | KDM2B (0.43) | ALDH1A1MEN1KMT2AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |