Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ARRB1 | P49407 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022374 | 0.96 | KDM4E (0.37) | EEDOPRM1OPRD1PARP10OPRK1 | |
| SCHEMBL4022370 | 0.96 | KDM4E (0.37) | EEDOPRM1OPRD1PARP10OPRK1 | |
| SCHEMBL4022581 | 0.94 | ALDH1A1 (0.35) | EEDOPRM1PARP10MEN1KMT2A | |
| SCHEMBL4022580 | 0.94 | ALDH1A1 (0.35) | EEDOPRM1PARP10MEN1KMT2A | |
| SCHEMBL5635105 | 0.92 | EED (0.31) | EEDOPRM1OPRD1DRD2HTR2A | |
| SCHEMBL4024477 | 0.89 | ABL1 (0.37) | EEDOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL4024473 | 0.89 | ABL1 (0.37) | EEDOPRM1OPRD1OPRK1MEN1 | |
| SCHEMBL4019982 | 0.89 | KMT2A (0.39) | EEDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4019987 | 0.89 | KMT2A (0.39) | EEDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4024035 | 0.89 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |