Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583304 | 0.95 | CNR1 (0.53) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4582680 | 0.95 | MEN1 (0.49) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4017530 | 0.88 | CNR1 (0.46) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4019718 | 0.86 | CNR1 (0.47) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4024310 | 0.85 | MEN1 (0.62) | CNR1CNR2KMT2AMEN1PAK1 | |
| SCHEMBL4025066 | 0.85 | ALDH1A1 (0.51) | CCNE1CDK2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4023745 | 0.85 | CNR1 (0.54) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4018789 | 0.85 | DRD2 (0.44) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4023469 | 0.84 | DRD2 (0.44) | CNR1CNR2CCNE1CDK2KMT2A | |
| SCHEMBL4020834 | 0.84 | PAK1 (0.60) | CNR1CNR2CCNE1CDK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |