Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19349268 | 0.75 | GAA (0.42) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL29455898 | 0.75 | GAA (0.42) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL21598733 | 0.74 | GLA (0.38) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL30254275 | 0.74 | GLA (0.38) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL21031807 | 0.74 | GLA (0.45) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL29601287 | 0.74 | GLA (0.45) | GLAPOLBGAATSHRPIK3CD | |
| SCHEMBL25258979 | 0.71 | GLA (0.42) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL909629 | 0.71 | PIK3CD (0.57) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL30254041 | 0.71 | PIK3CD (0.57) | GLAPOLBGAATSHRHPGD | |
| SCHEMBL19133107 | 0.71 | GLA (0.42) | GLAPOLBGAATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046775-A1 | N-(AMINOHETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012418-A1 | N-(AMINOHETEROARYL)-1H-INDOLE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2008-01-31 | — | — | WO | disclosed |