Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942190 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPTL3MBTL1S1PR1S1PR3 | |
| SCHEMBL4023069 | 0.81 | MAPT (0.34) | ALDH1A1MAPTL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL4023062 | 0.77 | MAPT (0.38) | ALDH1A1MAPTL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL4158477 | 0.76 | MAPT (0.60) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL4211551 | 0.75 | MAPT (0.59) | ALDH1A1MAPTL3MBTL1KDM4ETDP1 | |
| SCHEMBL4023072 | 0.75 | MAPT (0.40) | ALDH1A1MAPTTSHRMEN1HTT | |
| SCHEMBL3950434 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL3941329 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL3950369 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3950920 | 0.73 | ALDH1A1 (0.62) | ALDH1A1MAPTL3MBTL1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |