Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023064 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1L3MBTL1NPSR1MTNR1A | |
| SCHEMBL4211554 | 0.78 | MAPT (0.50) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3941334 | 0.77 | MAPT (0.49) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3950925 | 0.76 | MAPT (0.51) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL4038220 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3946900 | 0.74 | ALDH1A1 (0.49) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL4357340 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3950155 | 0.73 | ALDH1A1 (0.46) | MAPTALDH1A1L3MBTL1MITFNPSR1 | |
| SCHEMBL3943595 | 0.73 | HDAC3 (0.36) | MAPTALDH1A1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL3942258 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |