Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921293 | 0.82 | PDK2 (0.50) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL22767920 | 0.77 | THRB (0.65) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL29663083 | 0.76 | THRB (0.59) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL3245527 | 0.76 | THRB (0.59) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL66735 | 0.74 | THRB (1.00) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL4636492 | 0.74 | THRB (0.68) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL11469925 | 0.74 | THRB (1.00) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL30488775 | 0.74 | THRB (1.00) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL4023562 | 0.73 | THRB (0.64) | THRBTDP1KDM4ELMNAHTT | |
| SCHEMBL406841 | 0.72 | THRB (0.65) | THRBTDP1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098453-A1 | AZONIA BICYCLOALKANES AS M3 MUSCARINIC ACETYLCHOLIN RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | WO | disclosed |