Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757812 | 0.81 | ALDH1A1 (0.45) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL28828009 | 0.75 | MAOB (0.43) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL9559475 | 0.72 | ALDH1A1 (0.50) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL7450150 | 0.71 | KDM4E (0.48) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL17443006 | 0.70 | NPC1 (0.56) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL17442989 | 0.70 | NPC1 (0.56) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL4585652 | 0.69 | NPC1 (0.38) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL995326 | 0.69 | LTA4H (0.55) | RAB9ANPC1ATMMAOBRPS6KB2 | |
| SCHEMBL73268 | 0.69 | PIM1 (0.49) | RAB9ANPC1ATMMAOBADORA2A | |
| SCHEMBL25208482 | 0.68 | ALDH1A1 (0.53) | ATMMAOBALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488856-B2 | Compounds based on fluoranthene and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2009-02-10 | — | — | US | disclosed |