SCHEMBL4023372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4019844	0.86	KDR (0.51)	KDRFLT1LMNAMAPTMAPK1
	SCHEMBL4021986	0.83	KDR (0.54)	KDRFLT1NAMPT
	SCHEMBL4016021	0.83	SMN1; SMN2 (0.50)	KDRFLT1LMNAMAPTNAMPT
	SCHEMBL4018099	0.81	KDR (0.65)	KDRFLT1LMNAMAPTMAPK1
	SCHEMBL4018399	0.81	MAPT (0.48)	KDRLMNAMAPTNAMPTKMT2A
	SCHEMBL4023402	0.81	NPC1 (0.50)	KDRLMNAMAPTMAPK1KMT2A
	SCHEMBL4020953	0.80	KDR (0.53)	KDRFLT1NAMPTKMT2ANT5E
	SCHEMBL4018288	0.79	KDR (0.71)	KDRFLT1LMNAMAPTMAPK1
	SCHEMBL4019386	0.79	KDR (1.00)	KDRFLT1MAPTMAPK1NAMPT
	SCHEMBL4019971	0.79	KDR (0.78)	KDRFLT1MAPK1NAMPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.