SCHEMBL4018399

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4016021	0.84	SMN1; SMN2 (0.50)	MAPTPOLBGAATDP1RAB9A
	SCHEMBL4015806	0.84	L3MBTL1 (0.50)	MAPTALDH1A1POLBKDM4EGAA
	SCHEMBL4020953	0.83	KDR (0.53)	ALDH1A1POLBKDM4ERAB9ANPC1
	SCHEMBL4022400	0.81	KDR (0.66)	MAPTALDH1A1POLBKDM4EGAA
	SCHEMBL4023372	0.81	KDR (0.65)	MAPTKDM4ELMNAKDRKMT2A
	SCHEMBL4023402	0.80	NPC1 (0.50)	MAPTALDH1A1POLBGAARAB9A
	SCHEMBL4017609	0.80	KDR (0.67)	MAPTALDH1A1POLBKDM4EGAA
	SCHEMBL4020868	0.79	MAPT (0.50)	MAPTALDH1A1POLBKDM4EGAA
	SCHEMBL4019844	0.79	KDR (0.51)	MAPTALDH1A1POLBLMNAKDR
	SCHEMBL4015993	0.77	MAPT (0.50)	MAPTALDH1A1POLBKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.