SCHEMBL4019844

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4021986	0.87	KDR (0.54)	KDRNAMPTFLT1L3MBTL1
	SCHEMBL4023372	0.86	KDR (0.65)	KDRMAPTLMNAMAPK1NAMPT
	SCHEMBL4015571	0.82	L3MBTL1 (0.65)	KDRMAPTLMNAMAPK1NAMPT
	SCHEMBL4016021	0.81	SMN1; SMN2 (0.50)	KDRMAPTLMNANAMPTFLT1
	SCHEMBL4021315	0.80	KDR (0.75)	KDRMAPTNAMPTHIF1AEPAS1
	SCHEMBL4023402	0.79	NPC1 (0.50)	KDRMAPTLMNAMAPK1ALDH1A1
	SCHEMBL4018399	0.79	MAPT (0.48)	KDRMAPTLMNANAMPTL3MBTL1
	SCHEMBL4020953	0.78	KDR (0.53)	KDRNAMPTFLT1L3MBTL1ALDH1A1
	SCHEMBL4016774	0.78	KDR (0.76)	KDRNAMPTHIF1AEPAS1FLT1
	SCHEMBL4018837	0.75	KDR (0.58)	KDRMAPTNAMPTHIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.