Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027172 | 0.99 | GAA (0.47) | GAAL3MBTL1MAPTHPGDHTT | |
| SCHEMBL4031550 | 0.86 | TP53 (0.49) | GAAL3MBTL1MAPTLMNAALDH1A1 | |
| SCHEMBL2237399 | 0.85 | TLR8 (0.51) | GAAL3MBTL1MAPTHPGDHTT | |
| SCHEMBL4022786 | 0.82 | PDGFRB (0.51) | GAAMAPTP2RY1PDGFRBKDR | |
| SCHEMBL2237930 | 0.81 | P2RY1 (0.48) | GAAL3MBTL1MAPTHPGDHTT | |
| SCHEMBL4024155 | 0.78 | TP53 (0.42) | GAAMAPTHPGDHTTTDP1 | |
| SCHEMBL4023792 | 0.78 | GAA (0.44) | GAAMAPTNPSR1MAPK1LMNA | |
| SCHEMBL4024543 | 0.77 | ALK (0.43) | GAAL3MBTL1MAPTHPGDLMNA | |
| SCHEMBL4023413 | 0.74 | LMNA (0.41) | GAAL3MBTL1MAPTHPGDHTT | |
| SCHEMBL5583862 | 0.73 | KDR (0.55) | GAAL3MBTL1MAPTP2RY1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | claimed |
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | disclosed |