Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031550 | 0.92 | TP53 (0.49) | TP53MAPTLMNAPKMKDM4E | |
| SCHEMBL4023792 | 0.89 | GAA (0.44) | TP53MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL4023413 | 0.86 | LMNA (0.41) | TP53MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL4024543 | 0.85 | ALK (0.43) | TP53MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL4027172 | 0.79 | GAA (0.47) | MAPTLMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL4023504 | 0.78 | GAA (0.46) | MAPTLMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL4028969 | 0.74 | TP53 (0.50) | TP53MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL4027846 | 0.72 | TP53 (0.46) | TP53MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL4030543 | 0.71 | KMT2A (0.51) | TP53MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL4024174 | 0.69 | POLB (0.45) | MAPTLMNASMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | claimed |
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | disclosed |