SCHEMBL4023810

SCHEMBL4023810

CNCCCN1C[C@H](C(=O)c2cccc(O)c2)[C@H](c2cccc(F)c2C)[C@@H](c2[c]cccc2O)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM2B Q8NHM5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4774163 0.95 KDM2B (0.31) KDM2B
SCHEMBL4024736 0.87 DRD3 (0.34) KDM2B
SCHEMBL4021552 0.86 DRD3 (0.36) KDM2B
SCHEMBL4022123 0.85 RORC (0.41)
SCHEMBL4028221 0.85 KDM2B (0.32) KDM2B
SCHEMBL4778094 0.85 KDM2B (0.32) KDM2B
SCHEMBL4022033 0.85 KDM2B (0.32) KDM2B
SCHEMBL4022340 0.85 KDM1A (0.31) KDM2B
SCHEMBL4774673 0.85
SCHEMBL4020367 0.84 KDM2B (0.31) KDM2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572814-B2 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds CYTOKINETICS, INCORPORATED (US) 2009-08-11 US disclosed