Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.34 |
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | HTR1A | P08908 | 7/20 | 0.34 |
| ▸ | DRD1 | P21728 | 7/20 | 0.34 |
| ▸ | DRD4 | P21917 | 7/20 | 0.34 |
| ▸ | DRD5 | P21918 | 7/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021552 | 0.98 | DRD3 (0.36) | DRD3DRD2HTR1ADRD1DRD4 | |
| SCHEMBL4029451 | 0.94 | CARM1 (0.37) | KDM2BMEN1KMT2ACARM1PRMT6 | |
| SCHEMBL4749199 | 0.89 | MEN1 (0.34) | DRD3DRD2HTR1ADRD1DRD4 | |
| SCHEMBL4748997 | 0.89 | MEN1 (0.34) | DRD3DRD2HTR1ADRD1DRD4 | |
| SCHEMBL4028191 | 0.89 | KIF11 (0.35) | DRD3DRD2HTR1ADRD1DRD4 | |
| SCHEMBL4029040 | 0.89 | DRD3 (0.35) | DRD3DRD2HTR1ADRD1DRD4 | |
| SCHEMBL4023810 | 0.87 | KDM2B (0.31) | KDM2B | |
| SCHEMBL4024540 | 0.87 | MEN1 (0.35) | KDM2BMEN1KMT2AALDH1A1 | |
| SCHEMBL13720775 | 0.87 | MEN1 (0.35) | KDM2BMEN1KMT2AALDH1A1 | |
| SCHEMBL4024525 | 0.87 | MEN1 (0.35) | KDM2BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |