SCHEMBL4023980

SCHEMBL4023980

CC(C)(C)OC(=O)NCc1ccccc1I

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.51
KDM4A O75164 1/20 0.50
NAMPT P43490 2/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43
NQO2 P16083 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HDAC1 Q13547 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
MALT1 Q9UDY8 1/20 0.42
IDO1 P14902 1/20 0.42
AKT1 P31749 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30159605 0.89 KCNA5 (0.56) KCNA5KDM4ANAMPTHDAC10HDAC6
SCHEMBL8018113 0.89 KCNA5 (0.56) KCNA5KDM4ANAMPTHDAC10HDAC6
SCHEMBL20777604 0.85 NQO2 (0.56) KCNA5KDM4ANAMPTNQO2MALT1
SCHEMBL9118035 0.84 CYP3A4 (0.60) CA12CA1BCHE
Water SCHEMBL27502854 0.83 KCNA5 (0.50) KCNA5KDM4ANAMPTHDAC10HDAC6
SCHEMBL6874894 0.83 KCNA5 (0.52) KCNA5KDM4ANAMPTHDAC10HDAC6
SCHEMBL5792738 0.83 KCNA5 (0.52) KCNA5KDM4ANAMPTHDAC10HDAC6
SCHEMBL3124959 0.83 ALDH1A1 (0.55) KCNA5KDM4AL3MBTL1LMNAPOLB
SCHEMBL30454240 0.83 KCNA5 (0.52) KCNA5KDM4ANAMPTHDAC10HDAC6
SCHEMBL21481525 0.81 KCNA5 (0.51) KCNA5KDM4ANAMPTHDAC10HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 US disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 EP disclosed
WO-2023239906-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-12-14 WO disclosed
WO-2023239906-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-12-14 WO disclosed
US-9102665-B2 Cysteinyl leukotriene antagonists SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2015-08-11 US disclosed
US-9102665-B2 Cysteinyl leukotriene antagonists SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2015-08-11 US disclosed
US-20140155596-A1 CYSTEINYL LEUKOTRIENE ANTAGONISTS SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2014-06-05 US disclosed
US-20140155596-A1 CYSTEINYL LEUKOTRIENE ANTAGONISTS SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) 2014-06-05 US disclosed
US-7514266-B2 Synthetic receptors for the detection of analytes BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-04-07 US disclosed
US-7514266-B2 Synthetic receptors for the detection of analytes BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-04-07 US disclosed
US-20060024834-A1 Synthetic receptors for the detection of analytes NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 KCNA5 2406/4885KDM4A 4358/4885NAMPT 216/4885
US-20060024834-A1 Synthetic receptors for the detection of analytes FSHR, QRFPR, TACR1 KCNA5 3475/4885KDM4A 3818/4885NAMPT 4592/4885
US-20140155596-A1 CYSTEINYL LEUKOTRIENE ANTAGONISTS LTC4S, CYSLTR2, CYSLTR1 KCNA5 742/4885KDM4A 2105/4885NAMPT 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.