⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784001 | 0.79 | — | — | |
| SCHEMBL7162485 | 0.77 | — | — | |
| SCHEMBL4318092 | 0.77 | — | — | |
| SCHEMBL6432535 | 0.77 | KMT2A (0.54) | — | |
| SCHEMBL7042196 | 0.76 | PTPN2 (0.40) | — | |
| SCHEMBL4556834 | 0.74 | PRNP (0.45) | — | |
| SCHEMBL2928256 | 0.74 | — | — | |
| SCHEMBL10442 | 0.74 | — | — | |
| SCHEMBL15693485 | 0.73 | — | — | |
| SCHEMBL13741851 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212516-A1 | 2-PHENYL-6-HALO-QUINOXALINE DERIVATIVES AS CHAPERONE-MEDIATED AUTOPHAGY (CMA) MODULATORS FOR THE TREATMENT OF PARKINGSON'S DISEASE | Albert Einstein College of Medicine (US) | 2023-07-19 | — | — | EP | disclosed |
| WO-2009103007-A2 | STEROID HORMONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-08-20 | — | — | WO | disclosed |
| EP-1879892-A2 | 2-PYRROLIDONE DERIVATIVES AND THEIR USES FOR THE TREATMENT OF INFLAMMATORY CONDITIONS AND PAIN | XENON PHARMACEUTICALS INC. (CA) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006113875-A2 | 2 - PYRROLIDONE DERIVATIVES AND THEIR USES FOR THE TREATMENT OF INFLAMMATORY CONDITIONS AND PAIN | XENON PHARMACEUTICALS INC. (CA) | 2006-10-26 | — | — | WO | disclosed |