⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15693485 | 0.79 | — | — | |
| SCHEMBL1162100 | 0.78 | — | — | |
| SCHEMBL9145311 | 0.77 | ALDH1A1 (0.47) | — | |
| SCHEMBL10442 | 0.76 | — | — | |
| SCHEMBL1366984 | 0.76 | — | — | |
| SCHEMBL4556834 | 0.76 | PRNP (0.45) | — | |
| SCHEMBL14048458 | 0.76 | — | — | |
| SCHEMBL13940487 | 0.76 | GAA (0.45) | — | |
| SCHEMBL375957 | 0.76 | KMT2A (0.56) | — | |
| SCHEMBL13741851 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048897-B2 | Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20110166124-A1 | TRICYCLIC SPIROCYCLE DERIVATIVES AND METHODS OF USE | MCCORMICK KEVIN D | 2011-07-07 | — | — | US | disclosed |
| US-20110166124-A1 | TRICYCLIC SPIROCYCLE DERIVATIVES AND METHODS OF USE | MCCORMICK KEVIN D | 2011-07-07 | — | — | US | disclosed |
| EP-1251395-B1 | Silver halide photographic material containing a methine dye | FUJIFILM CORP (JP) | 2010-09-29 | — | — | EP | disclosed |
| EP-1964844-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1964844-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1964845-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1964845-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1967523-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1967523-B1 | New thiophen glycoside derivatives, method for their manufacture, medicines containing these compounds and their application | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| US-7101856-B2 | Thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| EP-1523488-A1 | NOVEL THIOPHENYLGLYCOSIDE DERIVATIVES, METHODS FOR PRODUCTION THEREOF, MEDICAMENTS COMPRISING SAID COMPOUNDS AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-20040138143-A1 | Novel thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
| WO-2004007517-A1 | NOVEL THIOPHENYLGLYCOSIDE DERIVATIVES, METHODS FOR PRODUCTION THEREOF, MEDICAMENTS COMPRISING SAID COMPOUNDS AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-22 | — | — | WO | disclosed |
| EP-1251395-A1 | Silver halide photographic material and methine dye | FUJI PHOTO FILM CO., LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-20020058216-A1 | Silver halide photographic material and methine dye | FUJI PHOTO FILM CO., LTD. | 2002-05-16 | — | — | US | disclosed |
| US-5201936-A | Substituted thieno[3,2-b]pyran-5,7-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| EP-0483582-A1 | Thieno[3,2-b]pyranones, process for their preparation, intermediates, their use in combatting parasites, their use as herbicides and plantgrowth regulators | BAYER AG (DE) | 1992-05-06 | — | — | EP | disclosed |
| US-5095032-A | PARASITICIDAL NEW SUBSTITUTED THIENOPYRANONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0411419-A2 | Substituted thienopyranones, process for their preparation and their use in combating parasites | BAYER AG (DE) | 1991-02-06 | — | — | EP | disclosed |