Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180242 | 0.86 | KDM4E (0.58) | PRNPPPARGNPSR1RXFP1NCOR2 | |
| SCHEMBL3621051 | 0.86 | DHODH (0.51) | PRNPPPARGNPSR1RXFP1NCOR2 | |
| SCHEMBL3375243 | 0.85 | MAPT (0.55) | PRNPPPARGNPSR1RXFP1NCOR2 | |
| SCHEMBL10983558 | 0.83 | RXFP1 (0.51) | PRNPPPARGNPSR1RXFP1NCOR2 | |
| SCHEMBL2654173 | 0.81 | KMT2A (0.54) | NPSR1ALDH1A1MAPK1HPGDKDM4E | |
| SCHEMBL17873718 | 0.81 | KMT2A (0.50) | HPGDKDM4EKMT2AMEN1POLB | |
| SCHEMBL13753345 | 0.77 | PKM (0.47) | PRNPPPARGNPSR1RXFP1NCOR2 | |
| SCHEMBL13753403 | 0.77 | PRNP (0.43) | PRNPPPARGNPSR1RXFP1NCOR2 | |
| SCHEMBL10442 | 0.76 | — | — | |
| SCHEMBL2928256 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101084235-A | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | claimed |
| WO-2016150937-A1 | METHOD FOR PREPARATION OF THIOPHENECARBONYL CHLORIDES | LONZA LTD (CH) | 2016-09-29 | — | — | WO | disclosed |
| CN-103087113-B | One class boracic heteronuclear complex of iridium and its preparation method and application | NANJING POST & TELECOMMUNICATION UNIV. (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103087113-A | Boracic heteronuclear iridium complex and preparation method and application thereof | UNIV NANJING POSTS & TELECOMM | 2013-05-08 | — | — | CN | disclosed |
| CN-102994071-A | Organic and inorganic hybridization phosphorescence silicon dioxide magnetic nanoparticle and preparation and applications thereof | UNIV NANJING POSTS & TELECOMM | 2013-03-27 | — | — | CN | disclosed |
| CN-101084235-B | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC | 2012-10-17 | — | — | CN | disclosed |
| EP-1572246-B1 | NOVEL COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES | GUERBET SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| CN-101084235-A | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | disclosed |
| EP-1572246-A2 | NOVEL COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES | GUERBET (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004058275-A2 | COMPOSITIONS OF MAGNETIC PARTICLES COVERED WITH GEM-BISPHOSPHONATE DERIVATIVES | GUERBET (FR) | 2004-07-15 | — | — | WO | disclosed |