SCHEMBL4024643

SCHEMBL4024643

CCN1/C(=C\C=O)C(C)(Cc2ccccc2)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.46
ITGB2 P05107 1/20 0.43
ICAM1 P05362 1/20 0.43
ITGAL P20701 1/20 0.43
ALDH1A1 P00352 6/20 0.39
MEN1 O00255 3/20 0.39
MAPT P10636 3/20 0.39
KMT2A Q03164 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GPR55 Q9Y2T6 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ELANE P08246 1/20 0.38
NPC1 O15118 1/20 0.36
USP2 O75604 1/20 0.36
S1PR2 O95136 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4022619 1.00 LMNA (0.46) LMNAHTTITGB2ICAM1ITGAL
SCHEMBL13651752 0.87 ITGB2 (0.41) LMNAHTTITGB2ICAM1ITGAL
SCHEMBL13877850 0.84 HTT (0.62) LMNAHTTITGB2ICAM1ITGAL
SCHEMBL4016799 0.84 PTGDR2 (0.40) LMNAHTTALDH1A1MEN1MAPT
SCHEMBL4016802 0.84 PTGDR2 (0.40) LMNAHTTALDH1A1MEN1MAPT
SCHEMBL11853151 0.80 HTT (0.65) LMNAHTTALDH1A1MEN1MAPT
SCHEMBL13966066 0.80 HTT (0.65) LMNAHTTALDH1A1MEN1MAPT
SCHEMBL11853161 0.80 HTT (0.65) LMNAHTTALDH1A1MEN1MAPT
SCHEMBL13657871 0.79 MAPT (0.44) LMNAHTTITGB2ICAM1ITGAL
SCHEMBL11848186 0.76 LMNA (0.48) LMNAHTTALDH1A1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090252013-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-08 US disclosed
US-20090252013-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-08 US disclosed
US-20090252013-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-08 US disclosed
EP-2050794-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF Mitsubishi Chemical Corporation (JP) 2009-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090252013-A1 HYDRAZIDE CHELATE COMPLEX COMPOUND, OPTICAL RECORDING MEDIUM USING THE COMPOUND AND RECORDING METHOD THEREOF KCNN2, KCNH2, KCNN1 LMNA 1854/4885HTT 1167/4885ITGB2 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.