Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4026848 | 0.95 | KDM4E (0.65) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| SCHEMBL765905 | 0.92 | KDM4E (0.76) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| Bromide SCHEMBL698678 | 0.90 | KDM4E (0.79) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| Bromide SCHEMBL27941533 | 0.90 | KDM4E (0.79) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| SCHEMBL28520864 | 0.90 | KDM4E (0.73) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL28760030 | 0.90 | KDM4E (0.73) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2527501 | 0.90 | KMT2A (0.73) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| Bromide SCHEMBL27941532 | 0.90 | KDM4E (0.73) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| SCHEMBL8825043 | 0.85 | KDM4E (0.72) | KDM4EKMT2AMEN1PABPC1RAB9A | |
| SCHEMBL13203515 | 0.81 | KDM4E (0.96) | KDM4EKMT2AMEN1PABPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150666-B2 | Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom | ADA FOUNDATION (US) | 2015-10-06 | — | — | US | claimed |
| WO-2009099824-A1 | HYDROLYTICALLY STABLE, HYDROPHILIC ADHESION-PROMOTING MONOMERS AND POLYMERS MADE THEREFROM | ADA FOUNDATION (US) | 2009-08-13 | — | — | WO | claimed |
| US-20090188622-A1 | Hydrolytically Stable, Hydrophilic Adhesion-Promoting Monomers and Polymers Made Therefrom | ADA FOUNDATION (US) | 2009-07-30 | — | — | US | claimed |
| EP-3183387-B1 | COMPOSITE COMPRISING FABRIC AND POLYAMPHOLYTE HYDROGEL AND PREPARATION METHOD THEREOF | UNIV HOKKAIDO NAT UNIV CORP (JP) | 2019-09-25 | — | — | EP | disclosed |
| US-20170258571-A1 | COMPOSITE COMPRISING FABRIC AND POLYAMPHOLYTE HYDROGEL AND PREPARATION METHOD THEREOF | UNIVERSITY OF MASSACHUSETTS | 2017-09-14 | — | — | US | disclosed |
| EP-3183387-A1 | COMPOSITE COMPRISING FABRIC AND POLYAMPHOLYTE HYDROGEL AND PREPARATION METHOD THEREOF | National University Corporation Hokkaido University (JP) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016027383-A1 | COMPOSITE COMPRISING FABRIC AND POLYAMPHOLYTE HYDROGEL AND PREPARATION METHOD THEREOF | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2016-02-25 | — | — | WO | disclosed |
| US-9150666-B2 | Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom | ADA FOUNDATION (US) | 2015-10-06 | — | — | US | disclosed |
| WO-2009099824-A1 | HYDROLYTICALLY STABLE, HYDROPHILIC ADHESION-PROMOTING MONOMERS AND POLYMERS MADE THEREFROM | ADA FOUNDATION (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090188622-A1 | Hydrolytically Stable, Hydrophilic Adhesion-Promoting Monomers and Polymers Made Therefrom | ADA FOUNDATION (US) | 2009-07-30 | — | — | US | disclosed |