Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27941533 | 1.00 | KDM4E (0.79) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| SCHEMBL765905 | 0.98 | KDM4E (0.76) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| Hydrochloric Acid SCHEMBL2527501 | 0.96 | KMT2A (0.73) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| Bromide SCHEMBL27941532 | 0.96 | KDM4E (0.73) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| Ammonia Solution, Strong SCHEMBL28760030 | 0.96 | KDM4E (0.73) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| SCHEMBL28520864 | 0.96 | KDM4E (0.73) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| Oxalic Acid SCHEMBL4024677 | 0.90 | KDM4E (0.67) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| SCHEMBL8825043 | 0.90 | KDM4E (0.72) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| Oxalic Acid SCHEMBL4026848 | 0.89 | KDM4E (0.65) | KDM4EKMT2AMEN1RAB9APABPC1 | |
| Bromide SCHEMBL8662013 | 0.89 | KDM4E (1.00) | KDM4EKMT2AMEN1RAB9APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200980-B | Method for synthesizing indolizine compound under catalysis of silver | 江苏师范大学 | 2022-11-04 | — | — | CN | claimed |
| US-10494661-B2 | Stabilizer for preserving biological samples | BGI SHENZHEN (CN) | 2019-12-03 | — | — | US | claimed |
| US-20180334703-A1 | Stabilizer for Preserving Biological Samples | BGI SHENZHEN (CN) | 2018-11-22 | — | — | US | claimed |
| EP-3252040-A1 | STABILIZER FOR PRESERVING BIOLOGICAL SAMPLES | BGI Shenzhen (CN) | 2017-12-06 | — | — | EP | claimed |
| US-9150666-B2 | Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom | ADA FOUNDATION (US) | 2015-10-06 | — | — | US | claimed |
| WO-2009099824-A1 | HYDROLYTICALLY STABLE, HYDROPHILIC ADHESION-PROMOTING MONOMERS AND POLYMERS MADE THEREFROM | ADA FOUNDATION (US) | 2009-08-13 | — | — | WO | claimed |
| US-20090188622-A1 | Hydrolytically Stable, Hydrophilic Adhesion-Promoting Monomers and Polymers Made Therefrom | ADA FOUNDATION (US) | 2009-07-30 | — | — | US | claimed |
| EP-1488277-A4 | SWITCHABLE ELECTRO-OPTICAL LAMINATES | AVERY DENNISON CORP (US) | 2006-08-16 | — | — | EP | claimed |
| US-6963435-B2 | Switchable electro-optical laminates | AVERY DENNISON CORPORATION (US) | 2005-11-08 | — | — | US | claimed |
| US-20050083564-A1 | Switchable electro-optical laminates | MALLYA PRAKASH (US) | 2005-04-21 | — | — | US | claimed |
| EP-1488277-A2 | SWITCHABLE ELECTRO-OPTICAL LAMINATES | AVERY DENNISON CORPORATION (US) | 2004-12-22 | — | — | EP | claimed |
| US-20030193709-A1 | Switchable electro-optical laminates | AVERY DENNISON CORPORATION | 2003-10-16 | — | — | US | claimed |
| WO-2003083523-A2 | SWITCHABLE ELECTRO-OPTICAL LAMINATES | AVERY DENNISON CORPORATION (US) | 2003-10-09 | — | — | WO | claimed |
| EP-0877298-B1 | Coated xerographic photographic paper | XEROX CORP (US) | 2001-08-29 | — | — | EP | claimed |
| US-5908723-A | Recording sheets | XEROX CORPORATION (US) | 1999-06-01 | — | — | US | claimed |
| US-5846637-A | Coated xerographic photographic paper | XEROX CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| EP-0877298-A2 | Coated xerographic photographic paper | Xerox Corporation (US) | 1998-11-11 | — | — | EP | claimed |
| JP-7070068-A | — | — | None | — | — | JP | disclosed |
| US-4069055-A | PRINTING INKS | GENERAL ELECTRIC COMPANY (US) | 1978-01-17 | — | — | US | disclosed |
| US-RE29153-E | HERBICIDES, INSECTICIDES | MONSANTO COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180334703-A1 | Stabilizer for Preserving Biological Samples | NEFM, TREH, RNASE1 | KDM4E 3996/4885KMT2A 3347/4885MEN1 1334/4885 |
| US-10494661-B2 | Stabilizer for preserving biological samples | NEFM, TREH, RNASE1 | KDM4E 3996/4885KMT2A 3347/4885MEN1 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.