Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16916721 | 0.91 | SMN1; SMN2 (0.50) | KDM4EL3MBTL1ALOX15TDP1RAB9A | |
| SCHEMBL27735106 | 0.83 | FGFR1 (0.49) | RAB9ASMN1; SMN2NPC1TP53LMNA | |
| SCHEMBL12397268 | 0.81 | KDM4E (0.48) | KDM4EL3MBTL1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL1137587 | 0.81 | SMN1; SMN2 (0.57) | KDM4EL3MBTL1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL1137830 | 0.81 | KDM4E (0.48) | KDM4EL3MBTL1ALOX15TDP1RAB9A | |
| SCHEMBL16916718 | 0.78 | KDM4E (0.49) | KDM4EL3MBTL1ALOX15TDP1RAB9A | |
| SCHEMBL28455254 | 0.77 | L3MBTL1 (0.53) | KDM4EL3MBTL1ALOX15TDP1RAB9A | |
| SCHEMBL16876611 | 0.77 | L3MBTL1 (0.53) | KDM4EL3MBTL1ALOX15TDP1RAB9A | |
| SCHEMBL24787416 | 0.76 | L3MBTL1 (0.52) | KDM4EL3MBTL1ALOX15TDP1RAB9A | |
| SCHEMBL6760896 | 0.75 | KDM4E (0.47) | KDM4EL3MBTL1ALOX15TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504001-B1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF SE (DE) | 2009-04-15 | — | — | EP | claimed |
| US-7320975-B2 | 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | claimed |
| US-20050107401-A1 | 2- (2-pyridyl) -5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | US | claimed |
| EP-1504001-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF Aktiengesellschaft (DE) | 2005-02-09 | — | — | EP | claimed |
| WO-2003070721-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | claimed |
| EP-1737843-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-1504001-B1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF SE (DE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1504001-B1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF SE (DE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1504001-B1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF SE (DE) | 2009-04-15 | — | — | EP | disclosed |
| US-7320975-B2 | 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320975-B2 | 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320975-B2 | 2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-22 | — | — | US | disclosed |
| US-20050107401-A1 | 2- (2-pyridyl) -5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | US | disclosed |
| US-20050107401-A1 | 2- (2-pyridyl) -5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1504001-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF Aktiengesellschaft (DE) | 2005-02-09 | — | — | EP | disclosed |
| EP-1504001-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF Aktiengesellschaft (DE) | 2005-02-09 | — | — | EP | disclosed |
| EP-1504001-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF Aktiengesellschaft (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003070721-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003070721-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003070721-A1 | 2-(2-PYRIDYL)-5-PHENYL-6-AMINOPYRIMIDINE, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION AND USE THEREOF FOR COMBATING NOXIOUS FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107401-A1 | 2- (2-pyridyl) -5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi | HAAO, HAO1, DAO | KDM4E 2544/4885L3MBTL1 429/4885ALOX15 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.