Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22573444 | 0.85 | PRKCI (0.58) | ALDH1A1TDP1F2F12 | |
| SCHEMBL2558755 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1KDM6BKDM4AKDM5C | |
| SCHEMBL30525582 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1KDM6BKDM4AKDM5C | |
| SCHEMBL24787419 | 0.83 | SMN1; SMN2 (0.51) | KDM4EL3MBTL1ALOX15NPC1RAB9A | |
| SCHEMBL22573273 | 0.83 | HPGDS (0.47) | KDM4EL3MBTL1ALOX15NPC1RAB9A | |
| SCHEMBL22574062 | 0.82 | GRM5 (0.54) | KDM4EL3MBTL1NPC1RAB9ATP53 | |
| SCHEMBL3220326 | 0.82 | HPGDS (0.51) | KDM4EL3MBTL1KDM6BKDM4AKDM5C | |
| SCHEMBL5264050 | 0.81 | ALDH1A1 (0.65) | KDM4ENPC1RAB9AALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL3217961 | 0.81 | HPGDS (0.50) | KDM4EL3MBTL1KDM6BKDM4AKDM5C | |
| SCHEMBL22573429 | 0.81 | HPGDS (0.67) | HPGDSGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759412-B2 | FOR PRODUCING DRUGS USED FOR THERAPY OF CARDIOVASCULAR DISEASES, STABLE OR UNSTABLE ANGINA PECTORIS, CORONARY HEART DISEASE, PRINZMETAL ANGINA, ACUTE CORONARY SYNDROME, HEART FAILURE, MYOCARDIAL INFARCTION, STROKE, THROMBOSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-06 | — | — | US | disclosed |