Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 8/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024816 | 0.92 | NCF1 (0.52) | PAK1DRD4HTR1ADRD2HTR2A | |
| SCHEMBL4019291 | 0.88 | PAK1 (0.63) | PAK1DRD4HTR1ADRD2HTR2A | |
| SCHEMBL4019755 | 0.85 | PAK1 (0.58) | PAK1DRD4HTR1ADRD2HTR2A | |
| SCHEMBL4581607 | 0.84 | PAK1 (0.65) | PAK1DRD4HTR1ADRD2HTR2A | |
| SCHEMBL4582879 | 0.82 | P2RX7 (0.58) | PAK1DRD4HTR1ADRD2HTR2A | |
| SCHEMBL4015953 | 0.81 | PAK1 (0.56) | PAK1DRD4MEN1KMT2AP2RX7 | |
| SCHEMBL4024830 | 0.81 | PAK1 (0.56) | PAK1DRD4MEN1KMT2AP2RX7 | |
| SCHEMBL4016289 | 0.81 | MEN1 (0.55) | PAK1DRD4MEN1KMT2AMALT1 | |
| SCHEMBL4020162 | 0.81 | DRD4 (0.55) | PAK1DRD4MEN1KMT2AMALT1 | |
| SCHEMBL4019702 | 0.81 | P2RX7 (0.54) | PAK1DRD4HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |