SCHEMBL4025864

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL172747	0.81	KDR (0.62)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL29370693	0.79	KDR (1.00)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL5076094	0.79	KDR (1.00)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL1414455	0.78	KDR (0.59)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL5082453	0.78	KDR (0.77)	KDRCHEK1RAB9ANPC1BRD4
	SCHEMBL935681	0.76	KDR (0.65)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL4020849	0.75	KDR (0.67)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL5208407	0.74	KDR (0.74)	KDRCHEK1RAB9ANPC1KDM4E
	SCHEMBL15520686	0.73	FFAR1 (0.37)	KDRCHEK1
	SCHEMBL15520027	0.73	MAPT (0.42)	KDRCHEK1KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.