Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026734 | 1.00 | HPGDS (0.34) | HPGDSMGLLMEN1KMT2APARP1 | |
| SCHEMBL4021956 | 0.91 | PARP1 (0.32) | HPGDSMGLLMEN1KMT2APARP1 | |
| SCHEMBL4022330 | 0.91 | PARP1 (0.32) | HPGDSMGLLMEN1KMT2APARP1 | |
| SCHEMBL4022318 | 0.91 | PARP1 (0.32) | HPGDSMGLLMEN1KMT2APARP1 | |
| SCHEMBL4022804 | 0.88 | KIF11 (0.33) | MGLLPARP1 | |
| SCHEMBL4022792 | 0.88 | KIF11 (0.33) | MGLLPARP1 | |
| SCHEMBL4797014 | 0.84 | — | — | |
| SCHEMBL4022881 | 0.84 | KIF11 (0.37) | MGLL | |
| SCHEMBL4022873 | 0.84 | KIF11 (0.37) | MGLL | |
| SCHEMBL4019683 | 0.83 | KIF11 (0.34) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | TP53, VHL, RB1 | HPGDS 17/4885MGLL 2929/4885MEN1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.