Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027969 | 0.88 | TACR1 (0.43) | TACR1NR3C1KDM1AMAOAMAOB | |
| SCHEMBL4028910 | 0.88 | TACR1 (0.43) | TACR1NR3C1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4021093 | 0.87 | TACR1 (0.42) | TACR1NR3C1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4026387 | 0.87 | TACR1 (0.42) | TACR1NR3C1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4029527 | 0.81 | CHRNB4 (0.43) | TACR1 | |
| SCHEMBL7821260 | 0.72 | SMN1; SMN2 (0.43) | CYP2D6OPRK1 | |
| SCHEMBL9375935 | 0.72 | TACR1 (0.58) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL9375929 | 0.72 | TACR1 (0.58) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL4027560 | 0.70 | TACR1 (0.53) | TACR1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL4020600 | 0.69 | TACR1 (0.52) | TACR1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338592-B1 | Novel 2-phenylpiperazine derivatives | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2009-01-21 | — | — | EP | claimed |