Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 7/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030106 | 0.90 | SCARB1 (0.61) | SCARB1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL13746624 | 0.84 | SCARB1 (0.60) | SCARB1KMT2AHSD17B10KDM4ERORC | |
| SCHEMBL4030252 | 0.83 | SCARB1 (0.70) | SCARB1ALDH1A1HSD17B10KDM4ERORC | |
| SCHEMBL4189175 | 0.82 | SCARB1 (0.69) | SCARB1ALDH1A1HSD17B10KDM4ERORC | |
| SCHEMBL4028758 | 0.82 | SCARB1 (0.72) | SCARB1HSD17B10RORCPTGDR2 | |
| SCHEMBL4024931 | 0.82 | SCARB1 (0.69) | SCARB1ALDH1A1HSD17B10KDM4ERORC | |
| SCHEMBL4030140 | 0.81 | SCARB1 (0.59) | SCARB1ALDH1A1ALOX15HSD17B10KDM4E | |
| SCHEMBL4029504 | 0.81 | SCARB1 (0.68) | SCARB1ALDH1A1HSD17B10KDM4ERORC | |
| SCHEMBL4195549 | 0.81 | SCARB1 (0.68) | SCARB1ALDH1A1HSD17B10KDM4ERORC | |
| SCHEMBL13746788 | 0.81 | SCARB1 (0.56) | SCARB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |