Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626707 | 0.88 | GLA (0.31) | GLAGAAPOLB | |
| SCHEMBL4021055 | 0.88 | ALDH1A1 (0.30) | — | |
| SCHEMBL2626704 | 0.85 | HPGD (0.40) | GAA | |
| SCHEMBL2626708 | 0.83 | GLA (0.33) | GLAGAAPOLB | |
| SCHEMBL4026861 | 0.76 | NPSR1 (0.34) | — | |
| SCHEMBL2121837 | 0.73 | HCRTR1 (0.35) | GLA | |
| SCHEMBL13757955 | 0.73 | AGTR2 (0.40) | — | |
| SCHEMBL11000182 | 0.73 | GLA (0.37) | GLAPOLB | |
| SCHEMBL4769330 | 0.71 | GLA (0.36) | GLAPOLB | |
| SCHEMBL27609241 | 0.71 | ALDH1A1 (0.39) | GLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485375-B1 | PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2009-06-17 | — | — | EP | disclosed |